Despotting in high bit depth?

[18fps]

Lately I have been using Didée's "possible primitive for spot removal":

o=last ox=o.width() oy=o.height()

osup = o.MSuper(pel=2,sharp=2)
bv1  = osup.MAnalyse(isb=true, delta=1,blksize=8,overlap=4,search=4)
fv1  = osup.MAnalyse(isb=false,delta=1,blksize=8,overlap=4,search=4) 
bc1  = o.MCompensate(osup,bv1)
fc1  = o.MCompensate(osup,fv1)

Interleave(fc1,o,bc1)
MedianblurT(0,0,0,1)   #  you can also use "Clense(reduceflicker=false)" instead
SelectEvery(3,1)

StackHorizontal(o,last)

I like it because it keeps most of the grain, (though it should be tweaked to better distinguish between scenes).
However now I'm working with dpx files (HD, 10 bits) and I'd like to keep the high bit depth. I think I can ingest the dpx into Avisynth with ffms2. With the high bit depth tools, and the available modified plugins, it could be possible to despot and export to 10 bits? I think there is a modified mvtools plugin but I don't think there is a High bit MedianblurT. With what it could be substituted?
Thank you!