[takla]

Oh, ok.

Edit:
PelRefine=true & UseSubShift=0 uses 5908MB

PelRefine=false & UseSubShift=1 uses 3731MB

Here is the sample

Not full "4K", cropped to 1600 pixels in height, but still.

by the way, can you tell me why my script crashes? I ended up testing with your settings instead.

function EZdenoise(clip Input, int "thSAD", int "thSADC", int "TR", int "BLKSize", int "Overlap", int "Pel")
{
thSAD = default(thSAD, 150)
thSADC = default(thSADC, thSAD)
TR = default(TR, 12)
BLKSize = default(BLKSize, 8)
Overlap = default(Overlap, 0)
Pel = default(Pel, 4)

Super = Input.MSuper(Pel=Pel, Chroma=true, Levels=1, PelRefine=false)
Multi_Vector = Super.MAnalyse(Multi=true, Delta=TR, BLKSize=BLKSize, Overlap=Overlap, Chroma=false, Levels=1, optSearchOption=5, optPredictorType=0)

Input.MDegrainN(Super, Multi_Vector, TR, thSAD=thSAD, thSAD2=int(float(thSAD*0.9)), thSADC=thSADC, thSADC2=int(float(thSADC*0.9)), UseSubShift=1)
}