It's possible to clean this?

[Bluedraft]

A big yellow blotch across 2 sec of the clip

Sample
https://drive.google.com/file/d/1Manhk4-lkVuR8Yia8KD75oO7M171crmv/view?usp=sharing

[poisondeathray]

Assuming you mean the top border, one way is bbmod(ctop=16) or adjust the value to your taste . You can use with Trim to apply to affected scenes only

[Bluedraft]

No, I'm talking about the yellow crap that appear suddenly crossing the boat for about 2 sec
https://i.ibb.co/4njYnzrC/sample-mkv-screenshoot.png (https://ibb.co/dwQLwFYX)

[Selur]

I doubt normal filtering will work for a 2 second 'glitch'.
You could probably:
a. manually create a mask for it
b. use some inpainting method for it.
so maybe InpaintDelogo (https://forum.doom9.org/showthread.php?t=176860) is up for the job.
(creating the mask is probably the tricky part)

Cu Selur

Ps.: had a quick go at it using Vapoursynth: https://www.mediafire.com/folder/mqpk0yjffsp05/inpaint
https://i.ibb.co/BV76X6dr/grafik.png (https://ibb.co/Gv1MKMBt)
(could be better with a better mask)

[Bluedraft]

The result in those screenshots looks great to me, I'll check it out. Thanks a lot Selur!