I've tryed to overclock my card to see the benefits.
Clock description: Core / Shader / Memory
Standard clocks
540 / 1188 / 700
Overclock Core and Shader
595 / 1404 / 700
Overclock All
595 / 1404 / 918
Overclocking only the Core and Shader clocks gives a ~4% performance increase, if I also overclock the memory it gives a ~9% performance increase.
So, with madVR, the performance increase with my card was directly proportional to the clocks increase.