Yikes. It's not too bad for small numbers of tiles, but it blows up really fast.
Using fixed QP 45, here's some results. Not a full BD-Rate analysis, but some food for thought. I used identical values for tile-column and tile-row for each of the below examples
Code:
row/column | bitrate | fps | vmaf average
0 | 4867 | 4.52 | 91.773
1 | 4923 | 4.94 | 91.759
2 | 5000 | 4.88 | 91.725
4 | 5346 | 4.88 | 91.676
6 | 5995 | 5.01 | 91.557
So, similar encoding quality across the board but with an enormous bitrate cost when using 6 columns + rows with 1080p, almost 23% more bits.
I imagine the impact would be less for UHD.