Not really. But you can use avsw.Eval inside vapoursynth to process something by avs script (declaring inputs from vapoursynth that can be used inside avisynth block of code) and then output result into vapoursynth.
clip = core.your.Source(file)
avs_script_part = """
clip
your avs code here
"""
clip2 = core.avsw.Eval(avs_script_part, clips=[clip], clip_names=["clip"])
clip2.set_output()
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